High-throughput screening for natural compound-based autophagy modulators reveals novel chemotherapeutic mode of action for arzanol

Autophagy is an intracellular recycling pathway with implications for intracellular homeostasis and cell survival. Its pharmacological modulation can aid chemotherapy by sensitizing cancer cells toward approved drugs and overcoming chemoresistance. Recent translational data on autophagy modulators s...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Deitersen, Jana, Berning, Lena, Stuhldreier, Fabian, Ceccacci, Sara, Schlütermann, David, Friedrich, Annabelle, Wu, Wenxian, Sun, Yadong, Böhler, Philip, Berleth, Niklas, Mendiburo, María José, Seggewiß, Sabine, Anand, Ruchika, Reichert, Andreas S., Monti, Maria Chiara, Proksch, Peter, Stork, Björn
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167120/
https://ncbi.nlm.nih.gov/pubmed/34059630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03830-5
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