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High-throughput screening for natural compound-based autophagy modulators reveals novel chemotherapeutic mode of action for arzanol

Autophagy is an intracellular recycling pathway with implications for intracellular homeostasis and cell survival. Its pharmacological modulation can aid chemotherapy by sensitizing cancer cells toward approved drugs and overcoming chemoresistance. Recent translational data on autophagy modulators s...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Deitersen, Jana, Berning, Lena, Stuhldreier, Fabian, Ceccacci, Sara, Schlütermann, David, Friedrich, Annabelle, Wu, Wenxian, Sun, Yadong, Böhler, Philip, Berleth, Niklas, Mendiburo, María José, Seggewiß, Sabine, Anand, Ruchika, Reichert, Andreas S., Monti, Maria Chiara, Proksch, Peter, Stork, Björn
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167120/
https://ncbi.nlm.nih.gov/pubmed/34059630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03830-5
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