Hydroxycarboxylic Acid Receptor 2, a Pleiotropically Linked Receptor for the Multiple Sclerosis Drug, Monomethyl Fumarate. Possible Implications for the Inflammatory Response

Monomethyl fumarate (MMF), metabolite of dimethyl fumarate (DMF), an immunosuppressive drug approved for the treatment of multiple sclerosis (MS), is a potent agonist for hydroxycarboxylic acid receptor 2 (HCAR2), eliciting signals that dampen cell activation or lead to inflammation such as the skin...

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Vydáno v:Front Immunol
Hlavní autoři: Parodi, Benedetta, Sanna, Alessia, Cedola, Alessia, Uccelli, Antonio, Kerlero de Rosbo, Nicole
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8167049/
https://ncbi.nlm.nih.gov/pubmed/34084164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.655212
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