Epithelial PBLD attenuates intestinal inflammatory response and improves intestinal barrier function by inhibiting NF-κB signaling

Intestinal barrier function defects and dysregulation of intestinal immune responses are two key contributory factors in the pathogenesis of ulcerative colitis (UC). Phenazine biosynthesis-like domain-containing protein (PBLD) was recently identified as a tumor suppressor in gastric cancer, hepatoce...

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Vydáno v:Cell Death Dis
Hlavní autoři: Chen, Shengbo, Liu, Hongbin, Li, Zhijun, Tang, Jingyi, Huang, Bing, Zhi, Fachao, Zhao, Xinmei
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8166876/
https://ncbi.nlm.nih.gov/pubmed/34059646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03843-0
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