Loading...
Elementary mechanisms of calmodulin regulation of Na(V)1.5 producing divergent arrhythmogenic phenotypes
In cardiomyocytes, Na(V)1.5 channels mediate initiation and fast propagation of action potentials. The Ca(2+)-binding protein calmodulin (CaM) serves as a de facto subunit of Na(V)1.5. Genetic studies and atomic structures suggest that this interaction is pathophysiologically critical, as human muta...
Na minha lista:
| Udgivet i: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2021
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8166197/ https://ncbi.nlm.nih.gov/pubmed/34021086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2025085118 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|