Chromatin remodeler Arid1a regulates subplate neuron identity and wiring of cortical connectivity

Loss-of-function mutations in chromatin remodeler gene ARID1A are a cause of Coffin-Siris syndrome, a developmental disorder characterized by dysgenesis of corpus callosum. Here, we characterize Arid1a function during cortical development and find unexpectedly selective roles for Arid1a in subplate...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Doyle, Daniel Z., Lam, Mandy M., Qalieh, Adel, Qalieh, Yaman, Sorel, Alice, Funk, Owen H., Kwan, Kenneth Y.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2021
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8166177/
https://ncbi.nlm.nih.gov/pubmed/34011608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2100686118
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