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Chromatin remodeler Arid1a regulates subplate neuron identity and wiring of cortical connectivity
Loss-of-function mutations in chromatin remodeler gene ARID1A are a cause of Coffin-Siris syndrome, a developmental disorder characterized by dysgenesis of corpus callosum. Here, we characterize Arid1a function during cortical development and find unexpectedly selective roles for Arid1a in subplate...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8166177/ https://ncbi.nlm.nih.gov/pubmed/34011608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2100686118 |
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