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Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches

Glioblastoma (GBM) displays marked cellular and metabolic heterogeneity that varies among cellular microenvironments within a tumor. Metabolic targeting has long been advocated as a therapy against many tumors including GBM, but how lipid metabolism is altered to suit different microenvironmental co...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Shakya, Sajina, Gromovsky, Anthony D., Hale, James S., Knudsen, Arnon M., Prager, Briana, Wallace, Lisa C., Penalva, Luiz O. F., Brown, H. Alex, Kristensen, Bjarne W., Rich, Jeremy N., Lathia, Justin D., Brown, J. Mark, Hubert, Christopher G.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8166002/
https://ncbi.nlm.nih.gov/pubmed/34059134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01205-7
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