Gain of CXCR7 function with mesenchymal stem cell therapy ameliorates experimental arthritis via enhancing tissue regeneration and immunomodulation

BACKGROUND: The major barriers to mesenchymal stem cell (MSC) therapy in rheumatoid arthritis (RA) are a low extent of tissue regeneration and insufficient immunomodulation after cell transplantation. In addition, the role of C-X-C chemokine receptor type 7 (CXCR7) and its mechanism of action in MSC...

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Publicat a:Stem Cell Res Ther
Autors principals: Wei, Sung-Tai, Huang, Yen-Chih, Chiang, Jung-Ying, Lin, Chia-Ching, Lin, Yu-Jung, Shyu, Woei-Cherng, Chen, Hui-Chen, Hsieh, Chia-Hung
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8164772/
https://ncbi.nlm.nih.gov/pubmed/34051857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02402-w
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