A double-blind placebo-controlled trial of minocycline on translocator protein distribution volume in treatment-resistant major depressive disorder

Gliosis is implicated in the pathophysiology of many neuropsychiatric diseases, including treatment-resistant major depressive disorder (TRD). Translocator protein total distribution volume (TSPO V(T)), a brain marker mainly reflective of gliosis in disease, can be measured using positron emission t...

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Veröffentlicht in:Transl Psychiatry
Hauptverfasser: Attwells, Sophia, Setiawan, Elaine, Rusjan, Pablo M., Xu, Cynthia, Kish, Stephen J., Vasdev, Neil, Houle, Sylvain, Santhirakumar, Apitharani, Meyer, Jeffrey H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8164633/
https://ncbi.nlm.nih.gov/pubmed/34052828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-021-01450-3
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