Monoamine Oxidase B Total Distribution Volume in the Prefrontal Cortex of Major Depressive Disorder: An [(11)C]SL25.1188 Positron Emission Tomography Study

IMPORTANCE: Monoamine oxidase B (MAO-B) is an important, high-density enzyme in the brain that generates oxidative stress by hydrogen peroxide production, alters mitochondrial function, and metabolizes nonserotonergic monoamines. Recent advances in positron emission tomography radioligand developmen...

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Detalhes bibliográficos
Publicado no:JAMA Psychiatry
Main Authors: Moriguchi, Sho, Wilson, Alan A., Miler, Laura, Rusjan, Pablo M., Vasdev, Neil, Kish, Stephen J., Rajkowska, Grazyna, Wang, Junming, Bagby, Michael, Mizrahi, Romina, Varughese, Ben, Houle, Sylvain, Meyer, Jeffrey H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2019
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551845/
https://ncbi.nlm.nih.gov/pubmed/30840042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamapsychiatry.2019.0044
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