Diet-induced obesity promotes infection by impairment of the innate antimicrobial defense function of dermal adipocyte progenitors

Infections are a major complication of obesity, but the mechanisms responsible for impaired defense against microbes are not well understood. Here, we found that adipocyte progenitors were lost from the dermis during diet-induced obesity (DIO) in humans and mice. The loss of adipogenic fibroblasts f...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Zhang, Ling-juan, Guerrero-Juarez, Christian F., Chen, Stella X., Zhang, Xiaowei, Yin, Meimei, Li, Fengwu, Wu, Shuai, Chen, Joyce, Li, Min, Liu, Yingzi, Jiang, Shang I. B., Hata, Tissa, Plikus, Maksim V., Gallo, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8164450/
https://ncbi.nlm.nih.gov/pubmed/33472955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.abb5280
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados