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PPFIA4 mutation: A second hit in POLG related disease?

Epilepsy in POLG related disease usually involves biallelic recessive mutations causing chronic neuronal loss and neuronal death. However, monoallelic POLG mutations have been reported in patients with neurological features such as seizures [1]. In these patients a second allele/gene was anticipated...

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Detalhes bibliográficos
Publicado no:Epilepsy Behav Rep
Main Authors: Sourbron, Jo, Jansen, Katrien, Aerts, Nele, Lagae, Lieven
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8164014/
https://ncbi.nlm.nih.gov/pubmed/34095804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebr.2021.100455
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