Alternatively spliced isoforms of AUF1 regulate a miRNA–mRNA interaction differentially through their YGG motif

Proper base-pairing of a miRNA with its target mRNA is a key step in miRNA-mediated mRNA repression. RNA remodelling by RNA-binding proteins (RBPs) can improve access of miRNAs to their target mRNAs. The largest isoform p45 of the RBP AUF1 has previously been shown to remodel viral or AU-rich RNA el...

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Vydáno v:RNA Biol
Hlavní autoři: Sänger, Lennart, Bender, Julian, Rostowski, Katja, Golbik, Ralph, Lilie, Hauke, Schmidt, Carla, Behrens, Sven-Erik, Friedrich, Susann
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8163432/
https://ncbi.nlm.nih.gov/pubmed/32924750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2020.1822637
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