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Palladium catalyzed carbonylative generation of potent, pyridine-based acylating electrophiles for the functionalization of arenes to ketones

We describe here the design of a palladium catalyzed route to generate aryl ketones via the carbonylative coupling of (hetero)arenes and aryl- or vinyl-triflates. In this, the use of the large bite angle Xantphos ligand on palladium provides a unique avenue to balance the activation of the relativel...

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Bibliographic Details
Published in:Chem Sci
Main Authors: Liu, Yi, Kaiser, Angela M., Arndtsen, Bruce A.
Format: Artigo
Language:Inglês
Published: The Royal Society of Chemistry 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8163404/
https://ncbi.nlm.nih.gov/pubmed/34123121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc03129a
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