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Structure of DNA polymerase ζ: capturing the getaway driver
During translesion synthesis, eukaryotic DNA polymerase ζ (zeta) carries out extension from a wide range of DNA lesions. In this issue, Malik et al. (2020) (1) present the cryo-EM structure of polymerase ζ and show how it catalyzes the extension step of translesion synthesis.
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| Udgivet i: | Nat Struct Mol Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8163099/ https://ncbi.nlm.nih.gov/pubmed/32843752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0502-9 |
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