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Chemical synthesis and biological activity of peptides incorporating an ether bridge as a surrogate for a disulfide bond

Disulfide bridges contribute to the definition and rigidity of polypeptides, but they are inherently unstable in reducing environments and in the presence of isomerases and nucleophiles. Strategies to address these deficiencies, ideally without significantly perturbing the structure of the polypepti...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Chem Sci
Egile Nagusiak: Zhao, Rui, Shi, Pan, Chen, Junyou, Sun, Shuaishuai, Chen, Jingnan, Cui, Jibin, Wu, Fangming, Fang, Gemin, Tian, Changlin, Shi, Jing, Bierer, Donald, Liu, Lei, Li, Yi-Ming
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Royal Society of Chemistry 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8163063/
https://ncbi.nlm.nih.gov/pubmed/34094161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc02374d
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