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Chemo-selective cross reaction of two enals via carbene-catalyzed dual activation

A dual catalytic chemo-selective cross-coupling reaction of two enals is developed. One enal (without α-substitution) is activated by an NHC catalyst to form an acylazolium enolate intermediate that undergoes Michael-type addition to another enal molecule bearing an alkynyl substituent. Mechanistic...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Peng, Xiaolin, Xu, Jun, Li, Tingting, Chi, Yonggui Robin, Jin, Zhichao
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8162827/
https://ncbi.nlm.nih.gov/pubmed/34123233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc03297b
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