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One-step synthesis of benzo[b]thiophenes by aryne reaction with alkynyl sulfides

An aryne reaction with alkynyl sulfides affording benzo[b]thiophenes is disclosed. A wide range of 3-substituted benzothiophenes were synthesized from easily available o-silylaryl triflates and alkynyl sulfides in a one-step intermolecular manner. The synthesis of diverse multisubstituted benzothiop...

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Pubblicato in:Chem Sci
Autori principali: Matsuzawa, Tsubasa, Hosoya, Takamitsu, Yoshida, Suguru
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society of Chemistry 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8162113/
https://ncbi.nlm.nih.gov/pubmed/34094234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc04450d
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