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Effects of monoclonal antibodies against amyloid-β on clinical and biomarker outcomes and adverse event risks: a systematic review and meta-analysis of phase III RCTs in Alzheimer’s disease

OBJECTIVE: To investigate the effects of monoclonal antibodies against Aβ on cognition, function, amyloid PET and other biomarkers, as well as risk for amyloid-related imaging abnormalities (ARIA) and other adverse events, in Alzheimer’s disease (AD). METHODS: Pubmed, Web of Science, ClinicalTrials....

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Bibliografiske detaljer
Udgivet i:Ageing Res Rev
Main Authors: Avgerinos, Konstantinos I., Ferrucci, Luigi, Kapogiannis, Dimitrios
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8161699/
https://ncbi.nlm.nih.gov/pubmed/33831607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.arr.2021.101339
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