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Increasing protein stability by engineering the n → π* interaction at the β-turn

Abundant n → π* interactions between adjacent backbone carbonyl groups, identified by statistical analysis of protein structures, are predicted to play an important role in dictating the structure of proteins. However, experimentally testing the prediction in proteins has been challenging due to the...

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Détails bibliographiques
Publié dans:Chem Sci
Auteurs principaux: Khatri, Bhavesh, Majumder, Puja, Nagesh, Jayashree, Penmatsa, Aravind, Chatterjee, Jayanta
Format: Artigo
Langue:Inglês
Publié: The Royal Society of Chemistry 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8161691/
https://ncbi.nlm.nih.gov/pubmed/34094214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc03060k
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