Occurrence of Accelerated Epigenetic Aging and Methylation Disruptions in Human Immunodeficiency Virus Infection Before Antiretroviral Therapy

BACKGROUND: Whether accelerated aging develops over the course of chronic human immunodeficiency virus (HIV) infection or can be observed before significant immunosuppression on is unknown. We studied DNA methylation in blood to estimate cellular aging in persons living with HIV (PLWH) before the in...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Infect Dis
Main Authors: Yang, Chen Xi, Schon, Emma, Obeidat, Ma’en, Kobor, Michael S, McEwen, Lisa, MacIsaac, Julie, Lin, David, Novak, Richard M, Hudson, Fleur, Klinker, Hartwig, Dharan, Nila, Horvath, Steve, Bourbeau, Jean, Tan, Wan, Sin, Don D, Man, S F Paul, Kunisaki, Ken, Leung, Janice M
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Major Articles and Brief Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8161637/
https://ncbi.nlm.nih.gov/pubmed/32959881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa599
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