Occurrence of Accelerated Epigenetic Aging and Methylation Disruptions in Human Immunodeficiency Virus Infection Before Antiretroviral Therapy

BACKGROUND: Whether accelerated aging develops over the course of chronic human immunodeficiency virus (HIV) infection or can be observed before significant immunosuppression on is unknown. We studied DNA methylation in blood to estimate cellular aging in persons living with HIV (PLWH) before the in...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Yang, Chen Xi, Schon, Emma, Obeidat, Ma’en, Kobor, Michael S, McEwen, Lisa, MacIsaac, Julie, Lin, David, Novak, Richard M, Hudson, Fleur, Klinker, Hartwig, Dharan, Nila, Horvath, Steve, Bourbeau, Jean, Tan, Wan, Sin, Don D, Man, S F Paul, Kunisaki, Ken, Leung, Janice M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8161637/
https://ncbi.nlm.nih.gov/pubmed/32959881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa599
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