Hypothermia is not therapeutic in a neonatal piglet model of inflammation-sensitized hypoxia–ischemia

BACKGROUND: Perinatal inflammation combined with hypoxia–ischemia (HI) exacerbates injury in the developing brain. Therapeutic hypothermia (HT) is standard care for neonatal encephalopathy; however, its benefit in inflammation-sensitized HI (IS-HI) is unknown. METHODS: Twelve newborn piglets receive...

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Gepubliceerd in:Pediatr Res
Hoofdauteurs: Martinello, Kathryn A., Meehan, Christopher, Avdic-Belltheus, Adnan, Lingam, Ingran, Mutshiya, Tatenda, Yang, Qin, Akin, Mustafa Ali, Price, David, Sokolska, Magdalena, Bainbridge, Alan, Hristova, Mariya, Tachtsidis, Ilias, Tann, Cally J., Peebles, Donald, Hagberg, Henrik, Wolfs, Tim G. A. M., Klein, Nigel, Kramer, Boris W., Fleiss, Bobbi, Gressens, Pierre, Golay, Xavier, Robertson, Nicola J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group US 2021
Onderwerpen:
Basic Science Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8160560/
https://ncbi.nlm.nih.gov/pubmed/34050269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41390-021-01584-6
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