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Benefits of Sustained Upregulated Unimolecular GLP-1 and CCK Receptor Signalling in Obesity-Diabetes

Combined activation of GLP-1 and CCK1 receptors has potential to synergistically augment the appetite-suppressive and glucose homeostatic actions of the individual parent peptides. In the current study, pancreatic beta-cell benefits of combined GLP-1 and CCK1 receptor upregulation were established,...

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Dettagli Bibliografici
Pubblicato in:Front Endocrinol (Lausanne)
Autori principali: Tanday, Neil, English, Andrew, Lafferty, Ryan A., Flatt, Peter R., Irwin, Nigel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8160446/
https://ncbi.nlm.nih.gov/pubmed/34054734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2021.674704
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