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Structures in G proteins important for subtype selective receptor binding and subsequent activation
G protein-coupled receptors (GPCRs) selectively couple to specific heterotrimeric G proteins comprised of four subfamilies in order to induce appropriate physiological responses. However, structural determinants in Gα subunits responsible for selective recognition by approximately 800 human GPCRs ha...
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| Publicado en: | Commun Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8160216/ https://ncbi.nlm.nih.gov/pubmed/34045638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02143-9 |
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