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Evolution of opposing regulatory interactions underlies the emergence of eukaryotic cell cycle checkpoints

In eukaryotes the entry into mitosis is initiated by activation of cyclin-dependent kinases (CDKs), which in turn activate a large number of protein kinases to induce all mitotic processes. The general view is that kinases are active in mitosis and phosphatases turn them off in interphase. Kinases a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hernansaiz-Ballesteros, Rosa D., Földi, Csenge, Cardelli, Luca, Nagy, László G., Csikász-Nagy, Attila
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159995/
https://ncbi.nlm.nih.gov/pubmed/34045495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90384-3
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