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Evolution of opposing regulatory interactions underlies the emergence of eukaryotic cell cycle checkpoints
In eukaryotes the entry into mitosis is initiated by activation of cyclin-dependent kinases (CDKs), which in turn activate a large number of protein kinases to induce all mitotic processes. The general view is that kinases are active in mitosis and phosphatases turn them off in interphase. Kinases a...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8159995/ https://ncbi.nlm.nih.gov/pubmed/34045495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90384-3 |
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