Loss of DLX3 tumor suppressive function promotes progression of SCC through EGFR-ERBB2 pathway

Cutaneous squamous cell carcinoma (cSCC) ranks second in the frequency of all skin cancers. The balance between keratinocyte proliferation and differentiation is disrupted in the pathological development of cSCC. DLX3 is a homeobox transcription factor which plays pivotal roles in embryonic developm...

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Veröffentlicht in:Oncogene
Hauptverfasser: Bajpai, Deepti, Mehdizadeh, Spencer, Uchiyama, Akihiko, Inoue, Yuta, Sawaya, Andrew, Overmiller, Andrew, Brooks, Stephen R., Hasneen, Kowser, Kellett, Meghan, Palazzo, Elisabetta, Motegi, Sei-ichiro, Yuspa, Stuart H., Cataisson, Christophe, Morasso, Maria I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159909/
https://ncbi.nlm.nih.gov/pubmed/33947961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01802-9
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