The homeoprotein DLX3 and tumor suppressor p53 co-regulate cell cycle progression and squamous tumor growth

Epidermal homeostasis depends on the coordinated control of keratinocyte cell cycle. Differentiation and the alteration of this balance can result in neoplastic development. Here we report on a novel DLX3-dependent network that constrains epidermal hyperplasia and squamous tumorigenesis. By integrat...

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Bibliografiske detaljer
Udgivet i:Oncogene
Main Authors: Palazzo, Elisabetta, Kellett, Meghan, Cataisson, Christophe, Gormley, Anna, Bible, Paul W., Pietroni, Valentina, Radoja, Nadezda, Hwang, Joonsung, Blumenberg, Miroslav, Yuspa, Stuart H., Morasso, Maria
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853298/
https://ncbi.nlm.nih.gov/pubmed/26522723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.380
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