The homeoprotein DLX3 and tumor suppressor p53 co-regulate cell cycle progression and squamous tumor growth

Epidermal homeostasis depends on the coordinated control of keratinocyte cell cycle. Differentiation and the alteration of this balance can result in neoplastic development. Here we report on a novel DLX3-dependent network that constrains epidermal hyperplasia and squamous tumorigenesis. By integrat...

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Publicado no:Oncogene
Main Authors: Palazzo, Elisabetta, Kellett, Meghan, Cataisson, Christophe, Gormley, Anna, Bible, Paul W., Pietroni, Valentina, Radoja, Nadezda, Hwang, Joonsung, Blumenberg, Miroslav, Yuspa, Stuart H., Morasso, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853298/
https://ncbi.nlm.nih.gov/pubmed/26522723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.380
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