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Chemical synthesis and immunological evaluation of new generation multivalent anticancer vaccines based on a Tn antigen analogue

Tumor associated carbohydrate antigens (TACAs), such as the Tn antigen, have emerged as key targets for the development of synthetic anticancer vaccines. However, the induction of potent and functional immune responses has been challenging and, in most cases, unsuccessful. Herein, we report the desi...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Pifferi, Carlo, Ruiz-de-Angulo, Ane, Goyard, David, Tiertant, Claire, Sacristán, Nagore, Barriales, Diego, Berthet, Nathalie, Anguita, Juan, Renaudet, Olivier, Fernández-Tejada, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159477/
https://ncbi.nlm.nih.gov/pubmed/34122907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc00544d
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