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Chimeric oligosaccharide conjugate induces opsonic antibodies against Streptococcus pneumoniae serotypes 19A and 19F

Streptococcus pneumoniae 19A (ST19A) and 19F (ST19F) are among the prevalent serotypes causing pneumococcal disease worldwide even after introduction of a 13-valent pneumococcal conjugate vaccine (PCV13). Synthetic glycoconjugate vaccines have defined chemical structures rather than isolated polysac...

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Dettagli Bibliografici
Pubblicato in:Chem Sci
Autori principali: Sanapala, Someswara Rao, Seco, Bruna M. S., Baek, Ju Yuel, Awan, Shahid I., Pereira, Claney L., Seeberger, Peter H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society of Chemistry 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159444/
https://ncbi.nlm.nih.gov/pubmed/34123020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc02230f
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