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Differentiating Aβ40 and Aβ42 in amyloid plaques with a small molecule fluorescence probe
Differentiating amyloid beta (Aβ) subspecies Aβ40 and Aβ42 has long been considered an impossible mission with small-molecule probes. In this report, based on recently published structures of Aβ fibrils, we designed iminocoumarin–thiazole (ICT) fluorescence probes to differentiate Aβ40 and Aβ42, amo...
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| Pubblicato in: | Chem Sci |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Royal Society of Chemistry
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8159352/ https://ncbi.nlm.nih.gov/pubmed/34122980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc02060e |
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