Ventricular, atrial, and outflow tract heart progenitors arise from spatially and molecularly distinct regions of the primitive streak

The heart develops from 2 sources of mesoderm progenitors, the first and second heart field (FHF and SHF). Using a single-cell transcriptomic assay combined with genetic lineage tracing and live imaging, we find the FHF and SHF are subdivided into distinct pools of progenitors in gastrulating mouse...

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Bibliografiske detaljer
Udgivet i:PLoS Biol
Main Authors: Ivanovitch, Kenzo, Soro-Barrio, Pablo, Chakravarty, Probir, Jones, Rebecca A., Bell, Donald M., Mousavy Gharavy, S. Neda, Stamataki, Despina, Delile, Julien, Smith, James C., Briscoe, James
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158918/
https://ncbi.nlm.nih.gov/pubmed/33999917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3001200
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