DDX3X Links NLRP11 to the Regulation of Type I Interferon Responses and NLRP3 Inflammasome Activation

Tight regulation of inflammatory cytokine and interferon (IFN) production in innate immunity is pivotal for optimal control of pathogens and avoidance of immunopathology. The human Nod-like receptor (NLR) NLRP11 has been shown to regulate type I IFN and pro-inflammatory cytokine responses. Here, we...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Kienes, Ioannis, Bauer, Sarah, Gottschild, Clarissa, Mirza, Nora, Pfannstiel, Jens, Schröder, Martina, Kufer, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158815/
https://ncbi.nlm.nih.gov/pubmed/34054816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.653883
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