Lack of WWC2 Protein Leads to Aberrant Angiogenesis in Postnatal Mice

The WWC protein family is an upstream regulator of the Hippo signalling pathway that is involved in many cellular processes. We examined the effect of an endothelium-specific WWC1 and/or WWC2 knock-out on ocular angiogenesis. Knock-outs were induced in C57BL/6 mice at the age of one day (P1) and eva...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Brücher, Viktoria Constanze, Egbring, Charlotte, Plagemann, Tanja, Nedvetsky, Pavel I., Höffken, Verena, Pavenstädt, Hermann, Eter, Nicole, Kremerskothen, Joachim, Heiduschka, Peter
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158494/
https://ncbi.nlm.nih.gov/pubmed/34070186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22105321
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