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Lack of WWC2 Protein Leads to Aberrant Angiogenesis in Postnatal Mice

The WWC protein family is an upstream regulator of the Hippo signalling pathway that is involved in many cellular processes. We examined the effect of an endothelium-specific WWC1 and/or WWC2 knock-out on ocular angiogenesis. Knock-outs were induced in C57BL/6 mice at the age of one day (P1) and eva...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Brücher, Viktoria Constanze, Egbring, Charlotte, Plagemann, Tanja, Nedvetsky, Pavel I., Höffken, Verena, Pavenstädt, Hermann, Eter, Nicole, Kremerskothen, Joachim, Heiduschka, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158494/
https://ncbi.nlm.nih.gov/pubmed/34070186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22105321
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