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Cephalotaxine Inhibits the Survival of Leukemia Cells by Activating Mitochondrial Apoptosis Pathway and Inhibiting Autophagy Flow

Cephalotaxine (CET) is a natural alkaloid with potent antileukemia effects. However, its underlying molecular mechanism has not been well understood. In this study, we verified that CET significantly inhibited the viability of various leukemia cells, including HL-60, NB4, Jurkat, K562, Raji and MOLT...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Liu, Tingting, Guo, Qiang, Zheng, Shuze, Liu, Yang, Yang, Heng, Zhao, Meimei, Yao, Lu, Zeng, Kewu, Tu, Pengfei
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158396/
https://ncbi.nlm.nih.gov/pubmed/34070111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26102996
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