Substance P Serves as a Balanced Agonist for MRGPRX2 and a Single Tyrosine Residue Is Required for β-Arrestin Recruitment and Receptor Internalization

Eitemau Tebyg

• Murepavadin, a Small Molecule Host Defense Peptide Mimetic, Activates Mast Cells via MRGPRX2 and MrgprB2
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  Cyhoeddwyd: (2021)
• MRGPRX2 Activation by Rocuronium: Insights from Studies with Human Skin Mast Cells and Missense Variants
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  Cyhoeddwyd: (2021)
• Identification of Gain and Loss of Function Missense Variants in MRGPRX2’s Transmembrane and Intracellular Domains for Mast Cell Activation by Substance P
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  Cyhoeddwyd: (2019)
• Roles of a Mast Cell–Specific Receptor MRGPRX2 in Host Defense and Inflammation
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  Cyhoeddwyd: (2020)
• Agonist-Specific Recruitment of Arrestin Isoforms Differentially Modify Delta Opioid Receptor Function
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  Cyhoeddwyd: (2016)