Thymoquinone-entrapped chitosan-modified nanoparticles: formulation optimization to preclinical bioavailability assessments

The major limitation with the oral administration of most of the phytochemicals is their low aqueous solubility and bioavailability. Thymoquinone (THQ) is one of the most widely used phytochemicals used to treat a variety of diseases. However, strong lipophilic characteristics limit its clinical app...

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Библиографические подробности
Опубликовано в: :Drug Deliv
Главные авторы: Rahat, Iqra, Imam, Syed Sarim, Rizwanullah, Md., Alshehri, Sultan, Asif, Mohammad, Kala, Chandra, Taleuzzaman, Mohamad
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2021
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158209/
https://ncbi.nlm.nih.gov/pubmed/34036860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2021.1927245
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