Thymoquinone-entrapped chitosan-modified nanoparticles: formulation optimization to preclinical bioavailability assessments

The major limitation with the oral administration of most of the phytochemicals is their low aqueous solubility and bioavailability. Thymoquinone (THQ) is one of the most widely used phytochemicals used to treat a variety of diseases. However, strong lipophilic characteristics limit its clinical app...

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Vydáno v:Drug Deliv
Hlavní autoři: Rahat, Iqra, Imam, Syed Sarim, Rizwanullah, Md., Alshehri, Sultan, Asif, Mohammad, Kala, Chandra, Taleuzzaman, Mohamad
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2021
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158209/
https://ncbi.nlm.nih.gov/pubmed/34036860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2021.1927245
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