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Direct Visualization of Amlodipine Intervention into Living Cells by Means of Fluorescence Microscopy

Amlodipine, a unique long-lasting calcium channel antagonist and antihypertensive drug, has weak fluorescence in aqueous solutions. In the current paper, we show that direct visualization of amlodipine in live cells is possible due to the enhanced emission in cellular environment. We examined the im...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Quentin, Christine, Gerasimaitė, Rūta, Freidzon, Alexandra, Atabekyan, Levon S., Lukinavičius, Gražvydas, Belov, Vladimir N., Mitronova, Gyuzel Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158129/
https://ncbi.nlm.nih.gov/pubmed/34070063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26102997
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