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High-Affinity Functional Fluorescent Ligands for Human β-Adrenoceptors

Visualization of the G-protein coupled receptor (GPCR) is of great importance for studying its function in a native cell. We have synthesized a series of red-emitting fluorescent probes targeting β-adrenergic receptor (βAR) that are compatible with confocal and Stimulated Emission Depletion (STED) m...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mitronova, Gyuzel Y., Lukinavičius, Gražvydas, Butkevich, Alexey N., Kohl, Tobias, Belov, Vladimir N., Lehnart, Stephan E., Hell, Stefan W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614969/
https://ncbi.nlm.nih.gov/pubmed/28951558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12468-3
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