Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies

Antibodies against coronavirus spike protein potently protect against infection and disease, but whether such protection can be extended to variant coronaviruses is unclear. This is exemplified by a set of iconic and well-characterized monoclonal antibodies developed after the 2003 SARS outbreak, in...

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Détails bibliographiques
Publié dans:MAbs
Auteurs principaux: Rouet, Romain, Mazigi, Ohan, Walker, Gregory J., Langley, David B., Sobti, Meghna, Schofield, Peter, Lenthall, Helen, Jackson, Jennifer, Ubiparipovic, Stephanie, Henry, Jake Y., Abayasingam, Arunasingam, Burnett, Deborah, Kelleher, Anthony, Brink, Robert, Bull, Rowena A., Turville, Stuart, Stewart, Alastair G., Goodnow, Christopher C., Rawlinson, William D., Christ, Daniel
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2021
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158043/
https://ncbi.nlm.nih.gov/pubmed/34024246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2021.1922134
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