AP-3–dependent targeting of flippase ATP8A1 to lamellar bodies suppresses activation of YAP in alveolar epithelial type 2 cells

Lamellar bodies (LBs) are lysosome-related organelles (LROs) of surfactant-producing alveolar type 2 (AT2) cells of the distal lung epithelium. Trafficking pathways to LBs have been understudied but are likely critical to AT2 cell homeostasis given associations between genetic defects of endosome to...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Kook, Seunghyi, Wang, Ping, Meng, Shufang, Jetter, Christopher S., Sucre, Jennifer M. S., Benjamin, John T., Gokey, Jason J., Hanby, Hayley A., Jaume, Alexa, Goetzl, Laura, Marks, Michael S., Guttentag, Susan H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2021
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157957/
https://ncbi.nlm.nih.gov/pubmed/33990468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2025208118
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia