Synthesis, Anticancer Screening of Some Novel Trimethoxy Quinazolines and VEGFR2, EGFR Tyrosine Kinase Inhibitors Assay; Molecular Docking Studies

A new series of 8-methoxy-2-trimethoxyphenyl-3-substituted quinazoline-4(3)-one compounds were designed, synthesized, and screened for antitumor activity against three cell lines, namely, Hela, A549, and MDA compared to docetaxel as reference drug. The molecular docking was performed using Autodock...

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發表在:Molecules
Main Authors: Altamimi, Abdulmalik S., El-Azab, Adel S., Abdelhamid, Sami G., Alamri, Mubarak A., Bayoumi, Ashraf H., Alqahtani, Safar M., Alabbas, Alhumaidi B., Altharawi, Ali I., Alossaimi, Manal A., Mohamed, Menshawy A.
格式: Artigo
語言:Inglês
出版: MDPI 2021
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157871/
https://ncbi.nlm.nih.gov/pubmed/34069962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26102992
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