Synthesis, Anticancer Screening of Some Novel Trimethoxy Quinazolines and VEGFR2, EGFR Tyrosine Kinase Inhibitors Assay; Molecular Docking Studies

A new series of 8-methoxy-2-trimethoxyphenyl-3-substituted quinazoline-4(3)-one compounds were designed, synthesized, and screened for antitumor activity against three cell lines, namely, Hela, A549, and MDA compared to docetaxel as reference drug. The molecular docking was performed using Autodock...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Altamimi, Abdulmalik S., El-Azab, Adel S., Abdelhamid, Sami G., Alamri, Mubarak A., Bayoumi, Ashraf H., Alqahtani, Safar M., Alabbas, Alhumaidi B., Altharawi, Ali I., Alossaimi, Manal A., Mohamed, Menshawy A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157871/
https://ncbi.nlm.nih.gov/pubmed/34069962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26102992
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