Investigating ADR mechanisms with Explainable AI: a feasibility study with knowledge graph mining

BACKGROUND: Adverse drug reactions (ADRs) are statistically characterized within randomized clinical trials and postmarketing pharmacovigilance, but their molecular mechanism remains unknown in most cases. This is true even for hepatic or skin toxicities, which are classically monitored during drug...

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Bibliographic Details
Published in:BMC Med Inform Decis Mak
Main Authors: Bresso, Emmanuel, Monnin, Pierre, Bousquet, Cédric, Calvier, François-Elie, Ndiaye, Ndeye-Coumba, Petitpain, Nadine, Smaïl-Tabbone, Malika, Coulet, Adrien
Format: Artigo
Language:Inglês
Published: BioMed Central 2021
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157660/
https://ncbi.nlm.nih.gov/pubmed/34039343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12911-021-01518-6
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