Investigating ADR mechanisms with Explainable AI: a feasibility study with knowledge graph mining

BACKGROUND: Adverse drug reactions (ADRs) are statistically characterized within randomized clinical trials and postmarketing pharmacovigilance, but their molecular mechanism remains unknown in most cases. This is true even for hepatic or skin toxicities, which are classically monitored during drug...

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Veröffentlicht in:BMC Med Inform Decis Mak
Hauptverfasser: Bresso, Emmanuel, Monnin, Pierre, Bousquet, Cédric, Calvier, François-Elie, Ndiaye, Ndeye-Coumba, Petitpain, Nadine, Smaïl-Tabbone, Malika, Coulet, Adrien
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157660/
https://ncbi.nlm.nih.gov/pubmed/34039343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12911-021-01518-6
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