Catalytic enantioselective arylative cyclizations of alkynyl 1,3-diketones by 1,4-rhodium(i) migration

The enantioselective synthesis of densely functionalized polycarbocycles by the rhodium(i)-catalyzed reaction of arylboronic acids with 1,3-diketones is described. The key step in these desymmetrizing domino addition–cyclization reactions is an alkenyl-to-aryl 1,4-Rh(i) migration, which enables aryl...

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Bibliographic Details
Published in:Chem Sci
Main Authors: Groves, Alistair, Sun, Jinwei, Parke, Hal R. I., Callingham, Michael, Argent, Stephen P., Taylor, Laurence J., Lam, Hon Wai
Format: Artigo
Language:Inglês
Published: The Royal Society of Chemistry 2020
Subjects:
Chemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157494/
https://ncbi.nlm.nih.gov/pubmed/34084335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc06309a
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