Overcoming chemotherapy resistance using pH-sensitive hollow MnO(2) nanoshells that target the hypoxic tumor microenvironment of metastasized oral squamous cell carcinoma

BACKGROUND: Smart nanoscale drug delivery systems that target acidic tumor microenvironments (TME) could offer controlled release of drugs and modulate the hypoxic TME to enhance cancer therapy. The majority of previously reported MnO(2) nanostructures are nanoparticles, nanosheets, or nanocomposite...

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Publicado en:J Nanobiotechnology
Autores principales: Zhou, Zhi-hang, Liang, Si-yuan, Zhao, Tong-chao, Chen, Xu-zhuo, Cao, Xian-kun, Qi, Ming, Huang, Ying-ying, Ju, Wu-tong, Yang, Meng, Zhu, Dong-wang, Pang, Yi-chuan, Zhong, Lai-ping
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157461/
https://ncbi.nlm.nih.gov/pubmed/34039370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-021-00901-9
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